Article

Chronic myeloid leukemia: cytogenetics and molecular biology’s part in the comprehension and management of the pathology and treatment evolution

2022-03-06

Abstract excerpt

Abstract Background Chronic myelogenous leukemia (CML) is a type of blood cancer that affects hematopoietic stem cells and is often characterized by the presence of the Philadelphia chromosome. The Philadelphia chromosome encodes for a protein with high tyrosine kinase activity which acts as a tumorigenic factor. Main body This review article reports an update on the pathophysiology of CML and highlights the role...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5b1d311d-fec4-57dd-bc0b-d10c3e4353c1
DOI: 10.1186/s43042-022-00248-2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Chronic myeloid leukemia: cytogenetics and molecular biology’s part in the comprehension and management of the pathology and treatment evolutionDOI 10.1186/s43042-022-00248-2Read

The role of cytogenetics and molecular biology in the diagnosis, treatment and monitoring of patients with chronic myeloid leukemiaSemantic proximity Read

Chronic myeloid leukemia with complex karyotypes: Prognosis and therapeutic approachesSemantic proximity Read

Cytogenetics and genomics in CML and other myeloproliferative neoplasms.Semantic proximity Read

Laboratory tools for diagnosis and monitoring response in patients with chronic myeloid leukemia.Semantic proximity Read

Chronic Myeloid Leukemia: Current Application of Cytogenetics and Molecular Testing for Diagnosis and TreatmentSemantic proximity Read

Chronic Myeloid Leukemia in 2007Semantic proximity Read

Chronic Myeloid Leukemia, from Pathophysiology to Treatment-Free Remission: A Narrative Literature ReviewSemantic proximity Read

Pathogenetic insight and prognostic information from standard and molecular cytogenetic studies in the BCR-ABL-negative myeloproliferative neoplasms (MPNs).Semantic proximity Read

Myeloid neoplasms in the World Health Organization 2016 classification.Semantic proximity Read

The Philadelphia chromosome in leukemogenesisSemantic proximity Read

Chronic myeloid leukemia: a type of MPNSemantic proximity Read

Natural course and biology of CML.Semantic proximity Read