Article
Laboratory tools for diagnosis and monitoring response in patients with chronic myeloid leukemia.
The Israel Medical Association journal : IMAJ - 1 Aug 2012
Tohami Tali, Nagler Arnon, Amariglio Ninette
Abstract excerpt
Chronic myeloid leukemia (CML) is a clonal hematological disease that represents 15-20% of all adult leukemia cases. The study and treatment of CML has contributed pivotal advances to translational medicine and cancer therapy. The discovery that a single chromosomal abnormality, the Philadelphia (Ph) chromosome, is responsible for the etiology of this disease was a milestone for treating and understanding CML....
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