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Article

Identification of chromosomal genes in Yersinia pestis that influence type III secretion and delivery of Yops into target cells.

PloS one - 1 Jan 2012

Houppert Andrew S, Kwiatkowski Elizabeth, Glass Elizabeth M, DeBord Kristin L, Merritt Peter M, Schneewind Olaf, Marketon Melanie M

Abstract excerpt

Pathogenic Yersinia species possess a type III secretion system, which is required for the delivery of effector Yop proteins into target cells during infection. Genes encoding the type III secretion machinery, its substrates, and several regulatory proteins all reside on a 70-Kb virulence plasmid. Genes encoded in the chromosome of yersiniae are thought to play important roles in bacterial perception of host...

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PMID: 22479512
DOI: 10.1371/journal.pone.0034039
PMCID: PMC3316589

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