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Article

Genetic and epigenetic alterations of familial pancreatic cancers.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2008

Brune Kieran, Hong Seung-Mo, Li Ang, Yachida Shinichi, Abe Tadayoshi, Griffith Margaret, Yang Dawei, Omura Noriyuki, Eshleman James, Canto Marcia, Schulick Rich, Klein Alison P, Hruban Ralph H, Iacobuzio-Donohue Christine, Goggins Michael

Abstract excerpt

BACKGROUND: Little is known about the genetic and epigenetic changes that contribute to familial pancreatic cancers. The aim of this study was to compare the prevalence of common genetic and epigenetic alterations in sporadic and familial pancreatic ductal adenocarcinomas. METHODS: DNA was isolat...

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Share to Carcinoma, Pancreatic Ductal
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins p21(ras)

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Source

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Identifiers

PMID: 19064568
DOI: 10.1158/1055-9965.EPI-08-0630
PMCID: PMC2664523

Genes

SMAD4
CLDN5
NPTX2
SPARC
TFPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19064568-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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