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Article

Genomic NGFB variation and multiple sclerosis in a case control study.

BMC medical genetics - 8 Dec 2008

Akkad Denis A, Kruse Niels, Arning Larissa, Gold Ralf, Epplen Jörg T

Abstract excerpt

BACKGROUND: Nerve growth factor beta (NGFB) is involved in cell proliferation and survival, and it is a mediator of the immune response. ProNGF, the precursor protein of NGFB, has been shown to induce cell death via interaction with the p75 neurotrophin receptor. In addition, this neurotrophin is differentially expressed in males and females. Hence NGFB is a good candidate to influence the course of multiple...

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Identifiers

PMID: 19063739
DOI: 10.1186/1471-2350-9-107
PMCID: PMC2613874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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