Article
Variation in the BDNF and NGFB genes in German atopic dermatitis patients.
Molecular and cellular probes - 1 Feb 2009
Hoffjan Sabine, Parwez Qumar, Petrasch-Parwez Elisabeth, Stemmler Susanne
Abstract excerpt
In humans, atopic dermatitis (AD) is believed to result from a complex interaction between genetic and environmental factors. Based on recent evidence, it has been proposed that neurotrophins play an important role in allergic inflammation. Levels of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) in blood have been found to be elevated and correlated positively with disease in AD patients....
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