Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila.

Cell - 28 Jun 1991

Karess R E, Chang X J, Edwards K A, Kulkarni S, Aguilera I, Kiehart D P

Abstract excerpt

Two independent approaches to understanding the molecular mechanism of cytokinesis have converged on the gene spaghetti-squash (sqh). A genetic screen for mitotic mutants identified sqh1, a mutation that disrupts cytokinesis, which was then cloned by transposon tagging. Independently, the gene that encodes the regulatory light chain of the biochemically defined nonmuscle myosin (MRLC-C) was also cloned. We show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to Cloning, Molecular

Share to Molecular Sequence Data

Share to Mutation

Share to Phenotype

Source

Identifiers

PMID: 1905980
DOI: 10.1016/0092-8674(91)90013-o

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila.PMID 1905980Read ↗

SALS, a WH2-domain-containing protein, promotes sarcomeric actin filament elongation from pointed ends during Drosophila muscle growth.Semantic proximity Read ↗

Molecular dissection of cytokinesis by RNA interference in Drosophila cultured cells.Semantic proximity Read ↗

Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function.Semantic proximity Read ↗

Troponin I is encoded in the haplolethal region of the Shaker gene complex of Drosophila.Semantic proximity Read ↗

Dominant Drop mutants are gain-of-function alleles of the muscle segment homeobox gene (msh) whose overexpression leads to the arrest of eye development.Semantic proximity Read ↗

Mutations in sticky lead to defective organization of the contractile ring during cytokinesis and are enhanced by Rho and suppressed by Rac.Semantic proximity Read ↗

The novel proteins Rng8 and Rng9 regulate the myosin-V Myo51 during fission yeast cytokinesis.Semantic proximity Read ↗

Cell-type-specific rescue of myosin function during Dictyostelium development defines two distinct cell movements required for culmination.Semantic proximity Read ↗

The S. pombe rlc1 gene encodes a putative myosin regulatory light chain that binds the type II myosins myo3p and myo2p.Semantic proximity Read ↗

Collier transcription in a single Drosophila muscle lineage: the combinatorial control of muscle identity.Semantic proximity Read ↗

LvsA, a protein related to the mouse beige protein, is required for cytokinesis in Dictyostelium.Semantic proximity Read ↗

Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.