Article
The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila.
Cell - 28 Jun 1991
Karess R E, Chang X J, Edwards K A, Kulkarni S, Aguilera I, Kiehart D P
Abstract excerpt
Two independent approaches to understanding the molecular mechanism of cytokinesis have converged on the gene spaghetti-squash (sqh). A genetic screen for mitotic mutants identified sqh1, a mutation that disrupts cytokinesis, which was then cloned by transposon tagging. Independently, the gene th...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Blotting, Southern
- Cell Division
- Chromosome Mapping
- Cloning, Molecular
- Drosophila melanogaster
- Gene Expression
- Genes
- Mitosis
- Molecular Sequence Data
- Mutation
- Myosins
- Nucleic Acid Hybridization
- Phenotype