Article
Potentially functional polymorphisms in the CASP7 gene contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population.
PloS one - 1 Jan 2013
Wang Meng-Yun, Zhu Mei-Ling, He Jing, Shi Ting-Yan, Li Qiao-Xin, Wang Ya-Nong, Li Jin, Zhou Xiao-Yan, Sun Meng-Hong, Wang Xiao-Feng, Yang Ya-Jun, Wang Jiu-Cun, Jin Li, Wei Qing-Yi
Abstract excerpt
BACKGROUND: Caspase 7 (CASP7) is an important regulator and executioner in the apoptosis pathway and plays a crucial role in cancer development and progression. However, few studies have evaluated associations between functional single nucleotide polymorphisms (SNPs) in the 3' untranslational region (UTR) of CASP7 and risk of gastric cancer. METHODS: In a case-control study of 1117 patients with gastric cancer...
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