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Article

Polymorphisms in GPCR genes: Their role in schizophrenia, autism diseases and response to antipsychotic treatment - A systematic review.

Progress in neuro-psychopharmacology & biological psychiatry - 2 Apr 2026

DelaCuesta-Barrutia Jon, Peñagarikano Olga, Ramos-Miguel Alfredo, Erdozain Amaia M

Abstract excerpt

Albeit different in their clinical presentations, schizophrenia (SZ) and autism spectrum disorder (ASD) share different features, with mounting evidence supporting a neurodevelopmental origin for both disorders and a common genetic susceptibility. Among associated genes, G protein-coupled receptors (GPCR) have frequently been related to both disorders. The aim of this systematic review is to gather evidence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41862122
DOI: 10.1016/j.pnpbp.2026.111669

Genes

DRD2
AVPR1A
DRD3
HTR2A
HTR2C
OXTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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