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Article

Promoter polymorphisms of IL2, IL4, and risk of gastric cancer in a high-risk Chinese population.

Molecular carcinogenesis - 1 Jul 2009

Wu Juan, Lu Yan, Ding Yan-bing, Ke Qiao, Hu Zhi-bin, Yan Zhi-gang, Xue Yan, Zhou Yan, Hua Zhao-lai, Shu Yong-qian, Liu Ping, Shen Jing, Xu Yao-chu, Shen Hong-bing

Abstract excerpt

Interleukin 2 (IL2) is a typical Th1 cytokine, and interleukin 4 (IL4) is an inducible Th2 cytokine. These cytokines are critical mediators of the Th1/Th2 balance and apoptosis potential and involved in the process of inflammation-mediated carcinogenesis in human organs, including the gastrointestinal tract. Therefore, we tested the hypothesis that functional variants in IL2 and IL4 were associated with risk of...

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PMID: 19058298
DOI: 10.1002/mc.20502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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