Article
Associations of genotypes and haplotypes of IL-17 with risk of gastric cancer in an eastern Chinese population.
Oncotarget - 13 Dec 2016
Zhou Fei, Qiu Li-Xin, Cheng Lei, Wang Meng-Yun, Li Jin, Sun Meng-Hong, Yang Ya-Jun, Wang Jiu-Cun, Jin Li, Wang Ya-Nong, Wei Qing-Yi
Abstract excerpt
Interleukin-17 plays a crucial role in inflammation-related carcinogenesis. We hypothesize that genetic variants in IL-17 are associated with gastric cancer (GCa) risk, and we genotyped five potentially functional single nucleotide polymorphisms (SNPs) (rs1974226 G > A, rs2275913 A > G, rs3819024 A > G, rs4711998 A > G, and rs8193036 C > T) of IL-17 in 1121 GCa patients and 1216 cancer-free controls in an eastern...