Article
Characterization of polymorphisms in the mannose-binding lectin gene promoter among human immunodeficiency virus 1 infected subjects.
Memorias do Instituto Oswaldo Cruz - 1 Nov 2008
Vallinoto A C R, Muto N A, Alves A E M, Machado L F A, Azevedo V N, Souza L L B, Ishak M O G, Ishak R
Abstract excerpt
The present study investigated the prevalence of mutations in the -550 (H/L) and -221 (X/Y) mannose-binding lectin (MBL) gene promoter regions and their impact on infection by human immunodeficiency virus 1 (HIV-1) in a population of 128 HIV-1 seropositive and 97 seronegative patients. The allele identification was performed through the sequence-specific primer polymerase chain reaction method, using primer...
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