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Article

A truncation in the aryl hydrocarbon receptor of the CRL:WI(Han) rat does not affect the developmental toxicity of TCDD.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Feb 2009

Jiang Tao, Bell David R, Clode Sally, Fan Ming Qi, Fernandes Alwyn, Foster Paul M D, Loizou George, MacNicoll Alan, Miller Brian G, Rose Martin, Tran Lang, White Shaun

Abstract excerpt

The aryl hydrocarbon receptor (AhR) is required for the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and so the AhR of CRL:WI and CRL:WI(Han) rats was characterized. Western blot showed AhR proteins of approximately 110 and approximately 97 kDa in individual rats from both strains. The AhR cDNA from a CRL:WI(Han) rat with the approximately 110-kDa protein revealed a sequence that was identical to that...

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PMID: 19056935
DOI: 10.1093/toxsci/kfn252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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