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Article

The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.

Biochemical and biophysical research communications - 16 Jan 2009

Park Jeehye, Lee Gina, Chung Jongkyeong

Abstract excerpt

The two Parkinson's disease (PD) genes, PTEN-induced kinase 1 (PINK1) and parkin, are linked in a common pathway which affects mitochondrial integrity and function. However, it is still not known what this pathway does in the mitochondria. Therefore, we investigated its physiological function in Drosophila. Because Drosophila PINK1 and parkin mutants show changes in mitochondrial morphology in both indirect...

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Source

Identifiers

PMID: 19056353
DOI: 10.1016/j.bbrc.2008.11.086

Genes

PINK1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.PMID 19056353Read ↗

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