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Article

Squalene synthase: a critical enzyme in the cholesterol biosynthesis pathway.

Clinical genetics - 1 Jan 2009

Do R, Kiss R S, Gaudet D, Engert J C

Abstract excerpt

High levels of plasma low-density lipoprotein cholesterol (LDL-C) are a significant risk factor for heart disease. Statins (3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors) have been extensively used to treat high-plasma LDL-C levels and are effective in preventing heart disease. However, statins can be associated with adverse side effects in some patients and do not work effectively in others. As an...

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Identifiers

PMID: 19054015
DOI: 10.1111/j.1399-0004.2008.01099.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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