Article
Role of potassium channel gene Kcnj10 in ethanol preference in C57bl/6J and DBA/2J mice.
Alcoholism, clinical and experimental research - 1 Mar 2009
Zou Shicong B, Weng Julia, Symons Melissa N, Singh Shiva M
Abstract excerpt
BACKGROUND: Inwardly-rectifying potassium channel protein Kir4.1 is encoded by Kcnj10 which maps to a quantitative trait locus on chromosome 1 for the voluntary alcohol consumption phenotype in mice. Kcnj10 brain expression differences have been established between ethanol-preferring C57Bl/6J and ethanol-avoiding BALB/cJ mice, but its differential expression in other tissues and strains have largely been...
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