Article
Development of SNP markers for C57BL/6N-derived mouse inbred strains.
Experimental animals - 1 Jan 2015
Mekada Kazuyuki, Hirose Mayu, Murakami Ayumi, Yoshiki Atsushi
Abstract excerpt
C57BL/6N inbred mice are used as the genetic background for producing knockout mice in large-scale projects worldwide; however, the genetic divergence among C57BL/6N-derived substrains has not been verified. Here, we identified novel single nucleotide polymorphisms (SNPs) specific to the C57BL/6NJ strain and selected useful SNPs for the genetic monitoring of C57BL/6N-derived substrains. Informative SNPs were...
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