Article
TP53 codon 72 polymorphism associated with prognosis in patients with advanced gastric cancer treated with paclitaxel and cisplatin.
Cancer chemotherapy and pharmacology - 1 Jul 2009
Kim Jong Gwang, Sohn Sang Kyun, Chae Yee Soo, Song Hong Suk, Kwon Ki-Young, Do Young Rok, Kim Min Kyoung, Lee Kyung Hee, Hyun Myung Soo, Lee Won Sik, Sohn Chang-Hak, Jung Joo Seop, Kim Gab Chul, Chung Ho Young, Yu Wansik
Abstract excerpt
PURPOSE: The present study analyzed the polymorphisms of apoptosis-related genes and their impact on the response to chemotherapy and survival of patients with advanced gastric cancer. PATIENTS AND METHODS: Fifty-seven patients with advanced gastric cancer treated with paclitaxel and cisplatin combination chemotherapy were enrolled in the present study. The genomic DNA was extracted from paraffin-embedded tissue,...
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