Article
Prognostic value of TP53 codon 72 polymorphism in advanced gastric adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2004
Zhang Zun-Wu, Laurence Nicola J, Hollowood Andrew, Newcomb Paul, Moorghen Moganaden, Gupta Jyoti, Feakins Roger, Farthing Michael J G, Alderson Derek, Holly Jeff
Abstract excerpt
PURPOSE: A common polymorphism of the tumor suppressor gene TP53 at codon 72 has been associated with human cancer susceptibility. The prognostic role of the polymorphism was assessed in 102 patients with advanced gastric adenocarcinoma. EXPERIMENTAL DESIGN: We followed up 102 consecutive Caucasian patients with advanced gastric adenocarcinoma for >5 years and determined the status of the TP53 codon 72...
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