Article
Sequence variations in 185/333 messages from the purple sea urchin suggest posttranscriptional modifications to increase immune diversity.
Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2008
Buckley Katherine M, Terwilliger David P, Smith L Courtney
Abstract excerpt
The 185/333 gene family is highly expressed in two subsets of immune cells in the purple sea urchin in response to immune challenges. The genes encode a surprisingly diverse set of transcripts, which is a function of the variable presence or absence of blocks of shared sequences, known as elements that generate element patterns. Diversity is also the result of a significant level of point mutations. Together,...
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