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Article

Short tandem repeats, segmental duplications, gene deletion, and genomic instability in a rapidly diversified immune gene family.

BMC genomics - 9 Nov 2016

Oren Matan, Barela Hudgell Megan A, D'Allura Brian, Agronin Jacob, Gross Alexandra, Podini Daniele, Smith L Courtney

Abstract excerpt

BACKGROUND: Genomic regions with repetitive sequences are considered unstable and prone to swift DNA diversification processes. A highly diverse immune gene family of the sea urchin (Strongylocentrotus purpuratus), called Sp185/333, is composed of clustered genes with similar sequence as well as several types of repeats ranging in size from short tandem repeats (STRs) to large segmental duplications. This...

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Identifiers

PMID: 27829352
DOI: 10.1186/s12864-016-3241-x
PMCID: PMC5103432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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