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Article

Unexpected diversity displayed in cDNAs expressed by the immune cells of the purple sea urchin, Strongylocentrotus purpuratus.

Physiological genomics - 12 Jul 2006

Terwilliger David P, Buckley Katherine M, Mehta Dhruti, Moorjani Priya G, Smith L Courtney

Abstract excerpt

We recently identified a unique family of transcripts, the 185/333 family, that comprise approximately 60% of the mRNAs induced by coelomocytes from the purple sea urchin in response to immunological challenge from lipopolysaccharide. An analysis of 81 full-length cDNAs revealed 67 unique nucleotide sequences encoding 64 different proteins. Diversity of the transcripts was based on 25 sequence blocks, or...

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PMID: 16837652
DOI: 10.1152/physiolgenomics.00011.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Unexpected diversity displayed in cDNAs expressed by the immune cells of the purple sea urchin, Strongylocentrotus purpuratus.PMID 16837652Read ↗

Distinctive expression patterns of 185/333 genes in the purple sea urchin, Strongylocentrotus purpuratus: an unexpectedly diverse family of transcripts in response to LPS, beta-1,3-glucan, and dsRNA.Semantic proximity Read ↗

Extraordinary diversity among members of the large gene family, 185/333, from the purple sea urchin, Strongylocentrotus purpuratus.Semantic proximity Read ↗

Sequence variations in 185/333 messages from the purple sea urchin suggest posttranscriptional modifications to increase immune diversity.Semantic proximity Read ↗

An Sp185/333 gene cluster from the purple sea urchin and putative microsatellite-mediated gene diversification.Semantic proximity Read ↗

The Sp185/333 immune response genes and proteins are expressed in cells dispersed within all major organs of the adult purple sea urchin.Semantic proximity Read ↗

The 185/333 gene family is a rapidly diversifying host-defense gene cluster in the purple sea urchin Strongylocentrotus purpuratus.Semantic proximity Read ↗

Characterization of the highly variable immune response gene family, He185/333, in the sea urchin, Heliocidaris erythrogramma.Semantic proximity Read ↗

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Diversification of innate immune genes: lessons from the purple sea urchin.Semantic proximity Read ↗

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