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Article

Genetic hypervariability in two distinct deuterostome telomerase reverse transcriptase genes and their early embryonic functions.

Molecular biology of the cell - 1 Jan 2009

Wells Trystan B, Zhang Guanglei, Harley Zenon, Vaziri Homayoun

Abstract excerpt

Functional proteins of complex eukaryotes within the same species are rather invariant. A single catalytic component of telomerase TERT is essential for an active telomerase complex that maintains telomeres. Surprisingly, we have identified two paralogous SpTERT-L and SpTERT-S genes with novel domains in Strongylocentrotus purpuratus (purple sea urchin). The SpTERT-S and SpTERT-L genes were differentially...

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Identifiers

PMID: 18946080
DOI: 10.1091/mbc.e08-07-0748
PMCID: PMC2613085

Genes

TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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