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Article

Genetic Variations in miR-30 Family Member Regulatory Regions Are Associated with Breast Cancer Risk in a Chinese Population.

BioMed research international - 1 Jan 2020

Zhou Jing, Wang Lijuan, Liu Sijun, Zhou Wen, Jiang Yue, Du Jiangbo, Dai Juncheng, Jin Guangfu, Ma Hongxia, Hu Zhibin, Chen Jiaping, Shen Hongbing

Abstract excerpt

MicroRNAs (miRNAs) of the miR-30 family are closely linked with tumor metastasis and play key roles in the complex malignant phenotypes of cancers by targeting many tumor-related genes. Deregulated expression of miR-30 family members has been commonly observed in breast cancer. However, associations between the genetic variants in the regulatory region of miR-30 family and the risk of breast cancer are still...

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PMID: 32309442
DOI: 10.1155/2020/8781348
PMCID: PMC7140140

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