Article
Analysis of p53 gene polymorphisms and protein over-expression in patients with breast cancer.
Pathology oncology research : POR - 1 Sept 2009
Akkiprik Mustafa, Sonmez Ozgur, Gulluoglu Bahadir M, Caglar Hale B, Kaya Handan, Demirkalem Pakize, Abacioglu Ufuk, Sengoz Meric, Sav Aydin, Ozer Ayse
Abstract excerpt
p53 polymorphic variants play an important role in the determination of tumor phenotype and characteristics in breast cancer. In this study, we examined three common polymorphisms in p53 gene and their haplotype combinations to assess their potential association with inherited predisposition to breast cancer development, in relations with the protein over-expression and patients' demographic data. A total of 99...
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