Article
P53 codon 72 polymorphism contributes to breast cancer risk: a meta-analysis based on 39 case-control studies.
Breast cancer research and treatment - 1 Apr 2010
Zhang Zhizhong, Wang Meilin, Wu Dongmei, Wang Miaomiao, Tong Na, Tian Yuanyuan, Zhang Zhengdong
Abstract excerpt
P53 is a tumor suppressor gene and plays important roles in the etiology of breast cancer. Studies revealing conflicting results on the role of p53 codon 72 polymorphism (G>C) on breast cancer risk led us to perform a meta-analysis to investigate this relationship. Thirty-nine published studies, including 26,041 breast cancer cases and 29,679 controls were identified. Odds ratios (ORs) and 95% confidence...
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