Article
Afamin is synthesized by cerebrovascular endothelial cells and mediates α‐tocopherol transport across an <i>in vitro</i> model of the blood–brain barrier
27 Nov 2008
Abstract excerpt
Alpha-tocopherol (alphaTocH), a member of the vitamin E family, is essential for normal neurological function. Despite the importance of alphaTocH transport into the CNS, transfer mechanisms across the blood-brain barrier (BBB) are not entirely clear. We here investigate whether afamin, a known alphaTocH-binding protein, contributes to alphaTocH transport across an in vitro model of the BBB consisting of primary...
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