Article

An in vitro model for vitamin A transport across the human blood-brain barrier

2023-04-12

Abstract excerpt

Vitamin A, supplied by the diet, is critical for brain health, but little is known about its delivery across the blood-brain barrier (BBB). Brain microvascular endothelial-like cells (BMECs) differentiated from human-derived induced pluripotent stem cells (iPSC) form a tight barrier that recapitulates many of the properties of the human BBB. We paired iPSC-derived BMECs with recombinant vitamin A serum transport p...

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Literature Corpus work: d4253b27-7e17-53d3-bbe4-7edc226fda6f
DOI: 10.1101/2023.04.11.536348

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