Article
How the global structure of protein interaction networks evolves.
Proceedings. Biological sciences - 7 Mar 2003
Wagner Andreas
Abstract excerpt
Two processes can influence the evolution of protein interaction networks: addition and elimination of interactions between proteins, and gene duplications increasing the number of proteins and interactions. The rates of these processes can be estimated from available Saccharomyces cerevisiae genome data and are sufficiently high to affect network structure on short time-scales. For instance, more than 100...
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