Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variants within the MMP3 gene are associated with Achilles tendinopathy: possible interaction with the COL5A1 gene.

British journal of sports medicine - 1 Jul 2009

Raleigh S M, van der Merwe L, Ribbans W J, Smith R K W, Schwellnus M P, Collins M

Abstract excerpt

OBJECTIVES: Sequence variation within the COL5A1 and TNC genes are known to associate with Achilles tendinopathy. The primary aim of this case-control genetic association study was to investigate whether variants within the matrix metalloproteinase 3 (MMP3) gene also contributed to both Achilles tendinopathy and Achilles tendon rupture in a Caucasian population. A secondary aim was to establish whether variants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Achilles Tendon
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Collagen Type V

Share to Epistasis, Genetic

Share to Gene Frequency

Share to Linkage Disequilibrium

Share to Matrix Metalloproteinase 3

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 19042922
DOI: 10.1136/bjsm.2008.053892

Genes

MMP3
TNC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variants within the MMP3 gene are associated with Achilles tendinopathy: possible interaction with the COL5A1 gene.PMID 19042922Read ↗

Association of the matrix metalloproteinase 3 (MMP3) single nucleotide polymorphisms with tendinopathies: case-control study in high-level athletes.Semantic proximity Read ↗

The MMP3 gene in musculoskeletal soft tissue injury risk profiling: A study in two independent sample groups.Semantic proximity Read ↗

Genetic risk factors for musculoskeletal soft tissue injuries.Semantic proximity Read ↗

Identification of Three Loci Associated with Achilles Tendon Injury Risk from a Genome-wide Association Study.Semantic proximity Read ↗

The COL5A1 gene and Achilles tendon pathology.Semantic proximity Read ↗

Polymorphisms within the COL5A1 gene and regulators of the extracellular matrix modify the risk of Achilles tendon pathology in a British case-control study.Semantic proximity Read ↗

The Role of COL1A1, COL5A1, ACTN3, MMP3, and GDF5 Gene Variants in Common Sports Injuries: Systematic Review of ACL Rupture, Achilles Tendinopathy, and Stress Fractures.Semantic proximity Read ↗

Association Between COL5a1, COL11a1, and COL11a2 Gene Variations and Rotator Cuff Tendinopathy in Young Athletes.Semantic proximity Read ↗

Investigation of variants within the COL27A1 and TNC genes and Achilles tendinopathy in two populations.Semantic proximity Read ↗

MMP3 single-nucleotide polymorphisms are associated with noncontact ACL injuries in competing high-level athletes.Semantic proximity Read ↗

Analysis of hereditary and medical risk factors in Achilles tendinopathy and Achilles tendon ruptures: a matched pair analysis.Semantic proximity Read ↗

Interactions between collagen gene variants and risk of anterior cruciate ligament rupture.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.