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Article

MMP3 single-nucleotide polymorphisms are associated with noncontact ACL injuries in competing high-level athletes.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jan 2024

Simunic-Briski Nina, Vrgoc Goran, Knjaz Damir, Jankovic Sasa, Dembic Zlatko, Lauc Gordan

Abstract excerpt

Matrix metalloproteinases (MMPs) play an important role in matrix remodeling, as well as in ligament integrity. Anterior cruciate ligament (ACL) rupture is a severe and frequent knee injury in sports. The aim of this study was to investigate polymorphisms within the MMP3 gene with the predisposition for noncontact ACL rupture in the Croatian professional athletes. One hundred eighty-seven (95 with ACL rupture...

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PMID: 37442641
DOI: 10.1002/jor.25663

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