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Article

Prognostic value of CXCR4 and FAK expression in acute myelogenous leukemia.

Leukemia research - 1 Jun 2009

Tavernier-Tardy Emmanuelle, Cornillon Jérôme, Campos Lydia, Flandrin Pascale, Duval Amélie, Nadal Nathalie, Guyotat Denis

Abstract excerpt

We analysed, by flow cytometry, the "adhesive" phenotype of acute myelogenous leukemia (AML) cells from 36 patients treated in our institution. In univariate analysis, the main prognostic factor for CR achievement was lower CXCR4 expression (p=0.03). Overall survival (OS) was negatively influenced by higher CXC chemokine receptor 4 (CXCR4) (p=0.01), very late antigen-4 (VLA-4) (p=0.01), and focal adhesion kinase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19042019
DOI: 10.1016/j.leukres.2008.10.014

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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