Article
The effects of homocysteine and MTHFR genotype on hip bone loss and fracture risk in elderly women.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Jul 2009
Zhu K, Beilby J, Dick I M, Devine A, Soós M, Prince R L
Abstract excerpt
SUMMARY: Few studies have evaluated the effects of homocysteine and methylenetetrahydrofolate reductase (MTHFR) genotype on age-related bone loss. In our 5-year cohort study with 1,213 women aged 70-85 years, high homocysteine is associated with greater hip bone loss but not fracture risk. The ef...
Topics
- Absorptiometry, Photon
- Aged
- Aged, 80 and over
- Bone Density
- Female
- Fractures, Bone
- Hip Joint
- Homocysteine
- Humans
- Methylenetetrahydrofolate Reductase (NADPH2)
- Osteoporosis, Postmenopausal
- Polymorphism, Single Nucleotide
- Prospective Studies
- Western Australia