Tumor protein 53 gene polymorphism, demographic attributes and associated risk factors among liver cancer patients in Calabar, Nigeria.

doi:10.1186/s12885-025-13803-y

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Article

Tumor protein 53 gene polymorphism, demographic attributes and associated risk factors among liver cancer patients in Calabar, Nigeria.

BMC cancer - 10 Mar 2025

Ekpenyong Blessing B, Ubi Godwin M, Kooffreh M E, Umoyen Anthony J, James Cecilia S, Ettah Ivon A, Etangetuk Nseabasi A, Effiom Bassey E, Okpechi Philip A, Ejue Bassey P, Ambo Ogar A

Abstract excerpt

Mutations in the TP53 gene had been attributed to the development of liver cancer. Hepatocellular carcinoma (HCC) and liver tumour are liver diseases having high mortality rates in several populations. There is no information on the TP53 gene polymorphism among liver diseases patients in Calabar, Nigeria. This study investigated the genetic polymorphism of TP53 among HCC and liver tumour in Calabar. This research...

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Topics

Humans
Female
Male
Liver Neoplasms
Nigeria
Adult

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Risk Factors

Carcinoma, Hepatocellular

Middle Aged

Gene Frequency

Case-Control Studies

Genetic Predisposition to Disease

Tumor Suppressor Protein p53

Polymorphism, Genetic

Genotype

Source

Open in PubMed Open full text

Identifiers

PMID: 40065269
DOI: 10.1186/s12885-025-13803-y
PMCID: PMC11892161

Genes

TP53

Provenance

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