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Article

A role for von Hippel-Lindau protein in pancreatic beta-cell function.

Diabetes - 1 Feb 2009

Puri Sapna, Cano David A, Hebrok Matthias

Abstract excerpt

OBJECTIVE: The Vhlh gene codes for the von Hippel-Lindau protein (VHL), a tumor suppressor that is a key player in the cellular response to oxygen sensing. In humans, a germline mutation in the VHL gene leads to the von Hippel-Lindau disease, a familial syndrome characterized by benign and malignant tumors of the kidney, central nervous system, and pancreas. RESEARCH DESIGN AND METHODS: We use Cre-lox...

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Identifiers

PMID: 19033400
DOI: 10.2337/db08-0749
PMCID: PMC2628617

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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