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Article

KEPE--a motif frequently superimposed on sumoylation sites in metazoan chromatin proteins and transcription factors.

Bioinformatics (Oxford, England) - 1 Jan 2009

Diella Francesca, Chabanis Sophie, Luck Katja, Chica Claudia, Ramu Chenna, Nerlov Claus, Gibson Toby J

Abstract excerpt

MOTIVATION: We noted that the sumoylation site in C/EBP homologues is conserved beyond the canonical consensus sequence for sumoylation. Therefore, we investigated whether this pattern might define a more general protein motif. RESULTS: We undertook a survey of the human proteome using a regular expression based on the C/EBP motif. This revealed significant enrichment of the motif using different Gene Ontology...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19033273
DOI: 10.1093/bioinformatics/btn594
PMCID: PMC2638927

Genes

EBP
FOS
HDAC4
HIPK1
HIPK2
JUN
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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