Article
Tumour necrosis factor alpha -308G/A gene polymorphism: lack of association with knee osteoarthritis in a Turkish population.
Clinical and experimental rheumatology - 1 Jan 2000
Sezgin M, Barlas I O, Ankarali H C, Altintaş Z M, Türkmen E, Gökdoğan T, Sahin G, Erdal M E
Abstract excerpt
OBJECTIVE: To study the association between TNFalpha-308 G/A polymorphism and susceptibility to and severity of knee osteoarthritis in a Turkish population. METHODS: Genomic DNA was obtained from 151 patients with knee osteoarthritis and 84 ethnically matched healthy controls. Polymerase chain reaction-restriction fragment length analysis was used to identify G/A polymorphism at position -308 in the promoter...
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