Determination of genotype combinations that can predict the outcome of the treatment of alcohol dependence using the 5-HT(3) antagonist ondansetron.

doi:10.1176/appi.ajp.2013.12091163

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Article

Determination of genotype combinations that can predict the outcome of the treatment of alcohol dependence using the 5-HT(3) antagonist ondansetron.

The American journal of psychiatry - 1 Sept 2013

Johnson Bankole A, Seneviratne Chamindi, Wang Xin-Qun, Ait-Daoud Nassima, Li Ming D

Abstract excerpt

OBJECTIVE: The authors previously reported that the 5'-HTTLPR-LL and rs1042173-TT (SLC6A4-LL/TT) genotypes in the serotonin transporter gene predicted a significant reduction in the severity of alcohol consumption among alcoholics receiving the 5-HT3 antagonist ondansetron. In this study, they explored additional markers of ondansetron treatment response in alcoholics by examining polymorphisms in the HTR3A and...

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Identifiers

PMID: 23897038
DOI: 10.1176/appi.ajp.2013.12091163
PMCID: PMC3809153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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