Article
Genomic imprinting effects on complex traits: a phenotype-based perspective.
Epigenetics - 1 Nov 2008
Wolf Jason B, Hager Reinmar, Cheverud James M
Abstract excerpt
Parent-of-origin dependent gene expression associated with genomic imprinting is expected to result in the phenotypic signature of a difference between the average phenotypes of the reciprocal heterozygotes. Quantitative genetic mapping approaches have exploited this phenotypic manifestation to identify putatively imprinted loci affecting the expression of 'complex' traits. By focusing on the phenotypic...
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