Article
Influence of genome imprinting on gene expression, phenotypic variations and development.
Human reproduction (Oxford, England) - 1 Jan 1991
Surani M A
Abstract excerpt
Genome imprinting confers functional differences on parental chromosomes as a result of the differences in epigenetic inheritance from parental germlines. Repressed and derepressed chromatin structures probably constitute the initial germline-dependent 'imprints'. Any subsequent modifications, such as DNA methylation, will be influenced by these initial epigenetic modifications. Hence, epigenetic modifications of...
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