Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of IgM and IgD expression in human B-lineage cells

1 May 1991

Abstract excerpt

IgD is thought to function primarily as an Ag receptor that is expressed, together with IgM, only on mature B lymphocytes. This differentiation stage-specific expression of IgD has been well characterized in mice, where delta mRNA is detected only in mature IgM/IgD B cells. Humans, in contrast to mice, have significant levels of serum IgD, suggesting that the regulation of this isotype might differ between the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunodeficiency and Autoimmune Disorders
Share to Monoclonal and Polyclonal Antibodies Research
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1902853
DOI: 10.4049/jimmunol.146.10.3314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of IgM and IgD expression in human B-lineage cellsPMID 1902853Read ↗

Regulation of IgM and IgD heavy chain gene expression: effect of abrogation of intergenic transcriptional termination.Semantic proximity Read ↗

Human IgM+IgD+ B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life.Semantic proximity Read ↗

Absence of surface IgD does not impair naive B cell homeostasis and memory B cell formation in humansSemantic proximity Read ↗

Evidence for a Large Compartment of IgM-Expressing Memory B Cells in HumansSemantic proximity Read ↗

Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development.Semantic proximity Read ↗

Artiodactyl IgD: The Missing LinkSemantic proximity Read ↗

Do CLL B cells correspond to naive or memory B-lymphocytes? Evidence for an active Ig switch unrelated to phenotype expression and Ig mutational pattern in B-CLL cells.Semantic proximity Read ↗

Insights into the function of IgD.Semantic proximity Read ↗

B cell differentiation and lymphocyte surface phenotype in late onset hypogammaglobulinaemia.Semantic proximity Read ↗

Molecular analysis of IgD-positive human germinal centres.Semantic proximity Read ↗

Identification of a novel immunoglobulin δ transcript and comparative analysis of the genes encoding IgD in Atlantic salmon and Atlantic halibutSemantic proximity Read ↗

Evolutionary variation of immunoglobulin mu heavy chain RNA processing pathways: origins, effects, and implications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.