Article
Insights into the function of IgD.
Developmental and comparative immunology - 1 Dec 2011
Edholm Eva-Stina, Bengten Eva, Wilson Melanie
Abstract excerpt
IgD, previously thought to be a recent addition to the immunoglobulin classes, has long been considered an enigmatic molecule. For example, it was debated if IgD had a specific function other than as an antigen receptor co-expressed with IgM on naive B cells and if it had an important role in mammalian immunity. However, during the past decade extensive sequencing of vertebrate genomes has shown that IgD homologs...
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