Global survey of genomic imprinting by transcriptome sequencing.

Abstract excerpt

Genomic imprinting restricts gene expression to a paternal or maternal allele. To date, approximately 90 imprinted transcripts have been identified in mouse, of which the majority were detected after intense interrogation of clusters of imprinted genes identified by phenotype-driven assays in mice with uniparental disomies [1]. Here we use selective priming and parallel sequencing to measure allelic bias in whole...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alleles
• Share to Chromosome Mapping