Article
A novel modulator domain of Ets transcription factors.
Genes & development - 1 Jun 1992
Wasylyk C, Kerckaert J P, Wasylyk B
Abstract excerpt
The ets gene family is composed of several oncogenes and codes for transcription factors. The Ets proteins have a similar sequence called the ets domain and bind to the core motif A/CGGAA. We show here that several members of the ets family have different trans-activating properties. The ets doma...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA
- DNA-Binding Proteins
- Humans
- Molecular Sequence Data
- Mutation
- Phosphorylation
- Precipitin Tests
- Protein Conformation
- Proto-Oncogene Protein c-ets-1
- Proto-Oncogene Protein c-ets-2
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-ets
- Repressor Proteins
- Trans-Activators
- Transcription Factors
- Transcriptional Activation
