Article
The genetic structure of the Turkish population reveals high levels of variation and admixture.
Proceedings of the National Academy of Sciences of the United States of America - 7 Sept 2021
Kars M Ece, Başak A Nazlı, Onat O Emre, Bilguvar Kaya, Choi Jungmin, Itan Yuval, Çağlar Caner, Palvadeau Robin, Casanova Jean-Laurent, Cooper David N, Stenson Peter D, Yavuz Alper, Buluş Hakan, Günel Murat, Friedman Jeffrey M, Özçelik Tayfun
Abstract excerpt
The construction of population-based variomes has contributed substantially to our understanding of the genetic basis of human inherited disease. Here, we investigated the genetic structure of Turkey from 3,362 unrelated subjects whose whole exomes (n = 2,589) or whole genomes (n = 773) were sequenced to generate a Turkish (TR) Variome that should serve to facilitate disease gene discovery in Turkey. Consistent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.