The genotoxicities of N-nitrosamines in Drosophila melanogaster in vivo: the correlation of mutagenicity in the wing spot test with the DNA damages detected by the DNA-repair test.

doi:10.1016/0165-1161(91)90012-w

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Article

The genotoxicities of N-nitrosamines in Drosophila melanogaster in vivo: the correlation of mutagenicity in the wing spot test with the DNA damages detected by the DNA-repair test.

Mutation research - 1 Apr 1991

Negishi T, Shiotani T, Fujikawa K, Hayatsu H

Abstract excerpt

The genotoxicities of a series of N-nitrosamines were assayed in the wing spot test and a new short-term test of Drosophila melanogaster. In the spot test, larval flies trans-heterozygous for the somatic cell markers mwh and flr3 were fed the test reagents and the wing hairs in adults were inspec...

Topics

Animals
Crosses, Genetic
DNA
DNA Damage
DNA Repair
Drosophila melanogaster
Female
Heterozygote
Male
Mutagenicity Tests
Nitrosamines
Phenotype

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