Article
Admixture mapping to identify spontaneous preterm birth susceptibility loci in African Americans.
Obstetrics and gynecology - 1 May 2011
Manuck Tracy A, Lai Yinglei, Meis Paul J, Sibai Baha, Spong Catherine Y, Rouse Dwight J, Iams Jay D, Caritis Steve N, O'Sullivan Mary J, Wapner Ronald J, Mercer Brian, Ramin Susan M, Peaceman Alan M
Abstract excerpt
OBJECTIVE: Preterm birth is 1.5 times more common in African American (17.8%) than European American women (11.5%), even after controlling for confounding variables. We hypothesize that genetic factors may account for this disparity and can be identified by admixture mapping. METHODS: This is a secondary analysis of women with at least one prior spontaneous preterm birth enrolled in a multicenter prospective...
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