Correlation of chromosomes 1p and 19q status and expressions of O⁶‐methylguanine DNA methyltransferase (MGMT), p53 and Ki‐67 in diffuse gliomas of World Health Organization (WHO) grades II and III: a clinicopathological study

Abstract excerpt

AIMS: The objective of the present study was to verify the correlation of chromosomes 1p and 19q status and expressions of O(6)-methylguanine DNA methyltransferase (MGMT), p53 and Ki-67 in diffuse gliomas of World Health Organization grades II and III. METHODS: A series of 146 diffuse gliomas, including 45 oligodendrogliomas, 42 oligoastrocytomas and 59 astrocytomas, were analysed by denaturing high-performance...

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