Article
[Expression of survivin and its significance in esophageal cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jan 2005
Zhu Hong-Xia, Wang Yi-Hua, Zhou Cui-Qi, Zhang Guo, Bai Jin-Feng, Quan Lan-Ping, Liu Zhi-Hua, Xu Ning-Zhi
Abstract excerpt
OBJECTIVE: To detect the expression of survivin in esophageal cancer and elucidate its function in esophageal cancer. METHODS: Expression of surviv in was detected in paired normal and tumor tissues from patients with esophageal cancer by semi-quantitative RT-PCR. A dominant-negative survivin (surT34A) was transfected into esophageal cancer EC9706 cells (EC9706surT34A). Colony formation and apoptosis of the...
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