Article
BicaudalD actively regulates microtubule motor activity in lipid droplet transport.
PloS one - 1 Jan 2008
Larsen Kristoffer S, Xu Jing, Cermelli Silvia, Shu Zhanyong, Gross Steven P
Abstract excerpt
BACKGROUND: A great deal of sub-cellular organelle positioning, and essentially all minus-ended organelle transport, depends on cytoplasmic dynein, but how dynein's function is regulated is not well understood. BicD is established to play a critical role in mediating dynein function-loss of BicD results in improperly localized nuclei, mRNA particles, and a dispersed Golgi apparatus-however exactly what BicD's...
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